ITM2A Antibody

ProSci
Product Code: PSI-62-450
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-62-450-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of ITM2A Antibody in K562 cell line lysates (35ug/lane)
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Western blot analysis of ITM2A using rabbit polyclonal ITM2A Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ITM2A gene (Lane 2).
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Western blot analysis of ITM2A Antibody in K562 cell line lysates (35ug/lane)
Western blot analysis of ITM2A using rabbit polyclonal ITM2A Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ITM2A gene (Lane 2).

Further Information

Additional Names:
Integral membrane protein 2A, Protein E25, ITM2A
Application Note:
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Background:
ITM2A is induced during thymocyte selection and T cell activation and causes downregulation of CD8 when overexpressed in CD4(+)CD8(+) double positive thymocytes.
Background References:
  • Gudbjartsson,D.F., et.al., Nat. Genet. 40 (5), 609-615 (2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ITM2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-49 amino acids from the N-terminal region of human ITM2A.
NCBI Gene ID #:
9452
NCBI Official Name:
Integral membrane protein 2A
NCBI Official Symbol:
ITM2A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Protein Accession #:
O43736
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
O43736
User NOte:
Optimal dilutions for each application to be determined by the researcher.