CAPN11 Antibody
Code | Size | Price |
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PSI-57-319-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Calpain-11, 3422-, Calcium-activated neutral proteinase 11, CANP 11, CAPN11
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Calpains constitute a family of intracellular
calcium-dependent cysteine proteases. There are eight members in
this superfamily. They consist of a variable 80 kDa subunit and an
invariant 30 kDa subunit. This calpain protein appears to have
protease activity and calcium-binding ability. A similar mouse
protein may play a functional role in spermatogenesis and in the
regulation of calcium-dependent signal transduction events during
meiosis.
Background References:
- Ben-Aharon, I., et al. Mol. Reprod. Dev. 73(6):767-773(2006)
- Dear, T.N., et al. Genomics 59(2):243-247(1999)
- Rojas, F.J., et al. Mol. Hum. Reprod. 5(6):520-526(1999)
- Saido, T.C., et al. FASEB J. 8(11):814-822(1994)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CAPN11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-438 amino acids from the Central region of human CAPN11.
NCBI Gene ID #:
11131
NCBI Official Name:
Calpain-11
NCBI Official Symbol:
CAPN11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
84 kDa
Protein Accession #:
Q9UMQ6
Protein GI Number:
218511961
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q9UMQ6
User NOte:
Optimal dilutions for each application to be determined by the researcher.