GMPR Antibody

ProSci
Product Code: PSI-56-717
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-717-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of GMPR using rabbit polyclonal GMPR Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GMPR gene.
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GMPR Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis of GMPR using rabbit polyclonal GMPR Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GMPR gene.
GMPR Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
GMP reductase 1, Guanosine 5'-monophosphate oxidoreductase 1, Guanosine monophosphate reductase 1, GMPR, GMPR1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.
Background References:
  • Chasman, D.I., et al. PLoS Genet.(11), E1000730 (2009) :
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
  • Mungall, A.J., et al. Nature 425(6960):805-811(2003)
  • Deng, Y., et al. Int. J. Biochem. Cell Biol. 34(9):1035-1050(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GMPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 238-267 amino acids from the C-terminal region of human GMPR.
NCBI Gene ID #:
2766
NCBI Official Name:
GMP reductase 1
NCBI Official Symbol:
GMPR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
P36959
Protein GI Number:
544455
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
P36959
User NOte:
Optimal dilutions for each application to be determined by the researcher.