CPZ Antibody

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ProSci
Product Code: PSI-62-316
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-62-316-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of CPZ Antibody in K562 cell line lysates (35ug/lane)
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Formalin-fixed and paraffin-embedded human placenta with CPZ Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of CPZ Antibody in K562 cell line lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human placenta with CPZ Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Documents

Further Information

Additional Names:
Carboxypeptidase Z, CPZ, 3417-, CPZ
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
CPZ is a member of the metallocarboxypeptidase family. This enzyme displays carboxypeptidase activity towards substrates with basic C-terminal residues. It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases.
Background References:
  • Fan,X., J. Histochem. Cytochem. 50 (11), 1509-1516 (2002)
  • Reznik,S.E., Cell. Mol. Life Sci. 58 (12-13), 1790-1804 (2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CPZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the N-terminal region of human CPZ.
NCBI Gene ID #:
8532
NCBI Official Name:
Carboxypeptidase Z
NCBI Official Symbol:
CPZ
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
74 kDa
Protein Accession #:
Q66K79
Protein GI Number:
296434423
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q66K79
User NOte:
Optimal dilutions for each application to be determined by the researcher.