CPN2 Antibody

ProSci
Product Code: PSI-56-915
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-915-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysate from HepG2 cell line, using CPN2 Antibody at 1:1000 at each lane.
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CPN2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis of lysate from HepG2 cell line, using CPN2 Antibody at 1:1000 at each lane.
CPN2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Carboxypeptidase N subunit 2, Carboxypeptidase N 83 kDa chain, Carboxypeptidase N large subunit, Carboxypeptidase N polypeptide 2, Carboxypeptidase N regulatory subunit, CPN2, ACBP
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit.
Background References:
  • Liu, T., et al. J. Proteome Res. 4(6):2070-2080(2005)
  • Bunkenborg, J., et al. Proteomics 4(2):454-465(2004)
  • Riley, D.A., et al. Genomics 50(1):105-108(1998)
  • Tan, F., et al. J. Biol. Chem. 265(1):13-19(1990)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CPN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human CPN2.
NCBI Gene ID #:
1370
NCBI Official Name:
Carboxypeptidase N subunit 2
NCBI Official Symbol:
CPN2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
P22792
Protein GI Number:
334302917
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
P22792
User NOte:
Optimal dilutions for each application to be determined by the researcher.