PAX7 Antibody
| Code | Size | Price |
|---|
| PSI-57-920-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Paired box protein Pax-7, HuP1, PAX7, HUP1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene is a member of the paired box (PAX) family of
transcription factors. Members of this gene family typically
contain a paired box domain, an octapeptide, and a paired-type
homeodomain. These genes play critical roles during fetal
development and cancer growth. The specific function of the paired
box 7 gene is unknown but speculated to involve tumor suppression
since fusion of this gene with a forkhead domain family member has
been associated with alveolar rhabdomyosarcoma. Three transcript
variants encoding different isoforms have been found for this gene.
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Williamson, D., et al. J. Clin. Oncol. 28(13):2151-2158(2010)
- Xynos, A., et al. Stem Cells 28(5):965-973(2010)
- Edwards, T.L., et al. Ann. Hum. Genet. 74(2):97-109(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PAX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-210 amino acids from the Central region of human PAX7.
NCBI Gene ID #:
5081
NCBI Official Name:
Paired box protein Pax-7
NCBI Official Symbol:
PAX7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
P23759
Protein GI Number:
8247951
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
P23759
User NOte:
Optimal dilutions for each application to be determined by the researcher.