GDF15 Antibody
| Code | Size | Price |
|---|
| PSI-56-501-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Growth/differentiation factor 15, GDF-15, Macrophage inhibitory cytokine 1, MIC-1, NSAID-activated gene 1 protein, NAG-1, NSAID-regulated gene 1 protein, NRG-1, Placental TGF-beta, Placental bone morphogenetic protein, Prostate differentiation factor, GDF15, MIC1, PDF, PLAB, PTGFB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are
members of the transforming growth factor-beta (see TGFB1; MIM
190180) superfamily and regulate tissue differentiation and
maintenance. They are synthesized as precursor molecules that are
processed at a dibasic cleavage site to release C-terminal domains
containing a characteristic motif of 7 conserved cysteines in the
mature protein.
Background References:
- Anand, I.S., et al. Circulation 122(14):1387-1395(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Staff, A.C., et al. Gynecol. Oncol. 118(3):237-243(2010)
- Roth, P., et al. Clin. Cancer Res. 16(15):3851-3859(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GDF15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human GDF15.
NCBI Gene ID #:
9518
NCBI Official Name:
Growth/differentiation factor 15
NCBI Official Symbol:
GDF15
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
Q99988
Protein GI Number:
313104195
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q99988
User NOte:
Optimal dilutions for each application to be determined by the researcher.