GLP2R Antibody
| Code | Size | Price |
|---|
| PSI-58-043-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Glucagon-like peptide 2 receptor, GLP-2 receptor, GLP-2-R, GLP-2R, GLP2R
Application Note:
For WB starting dilution is: 1:1000
Background:
The GLP2 receptor (GLP2R) is a G protein-coupled receptor
superfamily member closely related to the glucagon receptor ans
GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid
proglucagon-derived peptide produced by intestinal enteroendocrine
cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it
is derived from the proglucagon peptide encoded by the GCG gene.
GLP2 stimulates intestinal growth and upregulates villus height in
the small intestine, concomitant with increased crypt cell
proliferation and decreased enterocyte apoptosis. Moreover, GLP2
prevents intestinal hypoplasia resulting from total parenteral
nutrition. GLP2R, a G protein-coupled receptor superfamily member
is expressed in the gut and closely related to the glucagon
receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by
RefSeq].
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Festen, E.A., et al. Am. J. Gastroenterol. 105(2):395-402(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GLP2R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-248 amino acids from the Central region of human GLP2R.
NCBI Gene ID #:
9340
NCBI Official Name:
Glucagon-like peptide 2 receptor
NCBI Official Symbol:
GLP2R
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
O95838
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction,Growth Factor
Swissprot #:
O95838
User NOte:
Optimal dilutions for each application to be determined by the researcher.