SLAMF6 Antibody
| Code | Size | Price |
|---|
| PSI-58-240-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
SLAM family member 6, Activating NK receptor, NK-T-B-antigen, NTB-A, CD352, SLAMF6, KALI
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a type I transmembrane
protein, belonging to the CD2 subfamily of the immunoglobulin
superfamily. This encoded protein is expressed on Natural killer
(NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation
and associates with the Src homology 2 domain-containing protein
(SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs).
It functions as a coreceptor in the process of NK cell activation.
It can also mediate inhibitory signals in NK cells from X-linked
lymphoproliferative patients. Alternative splicing results in
multiple transcript variants encoding distinct isoforms.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SLAMF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-305 amino acids from the C-terminal region of human SLAMF6.
NCBI Gene ID #:
114836
NCBI Official Name:
SLAM family member 6
NCBI Official Symbol:
SLAMF6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
Q96DU3
Protein GI Number:
205830927
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
Q96DU3
User NOte:
Optimal dilutions for each application to be determined by the researcher.