LAIR1 Antibody
| Code | Size | Price |
|---|
| PSI-57-270-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, hLAIR1, CD305, LAIR1, CD305
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is an inhibitory receptor
found on peripheral mononuclear cells, including NK cells, T cells,
and B cells. Inhibitory receptors regulate the immune response to
prevent lysis of cells recognized as self. The gene is a member of
both the immunoglobulin superfamily and the leukocyte-associated
inhibitory receptor family. The gene maps to a region of 19q13.4
called the leukocyte receptor cluster, which contains at least 29
genes encoding leukocyte-expressed receptors of the immunoglobulin
superfamily.
Background References:
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Brondijk, T.H., et al. Blood 115(7):1364-1373(2010)
- Tang, X., et al. J. Immunol. 182(9):5446-5452(2009)
- Lebbink, R.J., et al. Matrix Biol. 28(4):202-210(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LAIR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the Central region of human LAIR1.
NCBI Gene ID #:
3903
NCBI Official Name:
Leukocyte-associated immunoglobulin-like receptor 1
NCBI Official Symbol:
LAIR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
31 kDa
Protein Accession #:
Q6GTX8
Protein GI Number:
74736490
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
Q6GTX8
User NOte:
Optimal dilutions for each application to be determined by the researcher.