RHD Antibody
| Code | Size | Price |
|---|
| PSI-59-029-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Blood group Rh(D) polypeptide, RHXIII, Rh polypeptide 2, RhPII, Rhesus D antigen, CD240D, RHD
Application Note:
For WB starting dilution is: 1:1000
Background:
The Rh blood group system is the second most clinically
significant of the blood groups, second only to ABO. It is also the
most polymorphic of the blood groups, with variations due to
deletions, gene conversions, and missense mutations. The Rh blood
group includes this gene, which encodes the RhD protein, and a
second gene that encodes both the RhC and RhE antigens on a single
polypeptide. The two genes, and a third unrelated gene, are found
in a cluster on chromosome 1. The classification of Rh-positive and
Rh-negative individuals is determined by the presence or absence of
the highly immunogenic RhD protein on the surface of erythrocytes.
Multiple transcript variants encoding different isoforms have been
found for this gene.
Background References:
- Flegr, J., et al. Folia Parasitol. 57(2):143-150(2010)
- Liu, H.C., et al. Biochim. Biophys. Acta 1800(6):565-573(2010)
- Schmid, P., et al. Transfusion 50(1):267-269(2010)
- Wang, X.D., et al. Eur. J. Clin. Invest. 39(7):607-617(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RHD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-201 amino acids from the Central region of human RHD.
NCBI Gene ID #:
6007
NCBI Official Name:
Blood group Rh(D) polypeptide
NCBI Official Symbol:
RHD
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
Q02161
Protein GI Number:
296452980
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
Q02161
User NOte:
Optimal dilutions for each application to be determined by the researcher.