C8B Antibody

ProSci
Product Code: PSI-60-701
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-701-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in CEM cell line lysates (35ug/lane).

Western blot analysis in CEM cell line lysates (35ug/lane).

Further Information

Additional Names:
Complement component C8 beta chain, Complement component 8 subunit beta, C8B
Application Note:
For WB starting dilution is: 1:1000
Background:
C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system. C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells. Patients with C8B deficiency are prone to bacteria infection.
Background References:
  • Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
  • Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
  • Davila, S., et al. Genes Immun. 11(3):232-238(2010)
  • Gancz, D., et al. Mol. Immunol. 47 (2-3), 310-317 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This C8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-422 amino acids from the C-terminal region of human C8B.
NCBI Gene ID #:
732
NCBI Official Name:
Complement component C8 beta chain
NCBI Official Symbol:
C8B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
Protein Accession #:
P07358
Protein GI Number:
20141201
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P07358
User NOte:
Optimal dilutions for each application to be determined by the researcher.