FCN1 Antibody
| Code | Size | Price |
|---|
| PSI-58-889-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ficolin-1, Collagen/fibrinogen domain-containing protein 1, Ficolin-A, Ficolin-alpha, M-ficolin, FCN1, FCNM
Application Note:
For WB starting dilution is: 1:1000
Background:
The ficolin family of proteins are characterized by the
presence of a leader peptide, a short N-terminal segment, followed
by a collagen-like region, and a C-terminal fibrinogen-like domain.
The collagen-like and the fibrinogen-like domains are also found
separately in other proteins such as complement protein C1q, C-type
lectins known as collectins, and tenascins. However, all these
proteins recognize different targets, and are functionally
distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in
the peripheral blood leukocytes, and has been postulated to
function as a plasma protein with elastin-binding activity.
Background References:
- Honore, C., et al. J. Leukoc. Biol. 88(1):145-158(2010)
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Gout, E., et al. J. Biol. Chem. 285(9):6612-6622(2010)
- Wittenborn, T., et al.Innate Immun 2(2):167-180(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the C-terminal region of human FCN1.
NCBI Gene ID #:
2219
NCBI Official Name:
Ficolin-1
NCBI Official Symbol:
FCN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
O00602
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
O00602
User NOte:
Optimal dilutions for each application to be determined by the researcher.