RFXAP Antibody
| Code | Size | Price |
|---|
| PSI-57-775-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Regulatory factor X-associated protein, RFX-associated protein, RFX DNA-binding complex 36 kDa subunit, RFXAP
Application Note:
For WB starting dilution is: 1:1000
Background:
Major histocompatibility (MHC) class II molecules are
transmembrane proteins that have a central role in development and
control of the immune system. The protein encoded by this gene,
along with regulatory factor X-associated ankyrin-containing
protein and regulatory factor-5, forms a complex that binds to the
X box motif of certain MHC class II gene promoters and activates
their transcription. Once bound to the promoter, this complex
associates with the non-DNA-binding factor MHC class II
transactivator, which controls the cell type specificity and
inducibility of MHC class II gene expression. Mutations in this
gene have been linked to bare lymphocyte syndrome type II,
complementation group D. Transcript variants utilizing different
polyA signals have been found for this gene.
Background References:
- Laird, K.M., et al. J. Mol. Biol. 403(1):40-51(2010)
- Bushway, M., et al. Immunogenetics 62(2):109-116(2010)
- Briggs, L., et al. Proteins 76(3):655-664(2009)
- Garvie, C.W., et al. Biochim. Biophys. Acta 1779(12):797-804(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This RFXAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-225 amino acids from the C-terminal region of human RFXAP.
NCBI Gene ID #:
5994
NCBI Official Name:
Regulatory factor X-associated protein
NCBI Official Symbol:
RFXAP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
O00287
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
O00287
User NOte:
Optimal dilutions for each application to be determined by the researcher.