CD68/CD68 Antibody
| Code | Size | Price |
|---|
| PSI-59-170-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Macrosialin, Gp110, CD68, CD68
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a 110-kD transmembrane glycoprotein that
is highly expressed by human monocytes and tissue macrophages. It
is a member of the lysosomal/endosomal-associated membrane
glycoprotein (LAMP) family. The protein primarily localizes to
lysosomes and endosomes with a smaller fraction circulating to the
cell surface. It is a type I integral membrane protein with a
heavily glycosylated extracellular domain and binds to tissue- and
organ-specific lectins or selectins. The protein is also a member
of the scavenger receptor family. Scavenger receptors typically
function to clear cellular debris, promote phagocytosis, and
mediate the recruitment and activation of macrophages. Alternative
splicing results in multiple transcripts encoding different
isoforms.
Background References:
- Leonarduzzi, G., et al. Mol Nutr Food Res 54 SUPPL 1, S31-S41 (2010) :
- Strojnik, T., et al. Anticancer Res. 29(8):3269-3279(2009)
- Sayed, S., et al. EurVasc Endovasc Surg 38(1):20-25(2009)
- Suzuki, Y., et al. IntRheum Dis 12(1):7-13(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CD68/CD68 (kpi) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-237 amino acids from the Central region of human CD68/CD68 (kpi).
NCBI Gene ID #:
968
NCBI Official Name:
Macrosialin
NCBI Official Symbol:
CD68
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
P34810
Protein GI Number:
147744552
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P34810
User NOte:
Optimal dilutions for each application to be determined by the researcher.