CD226 Antibody

ProSci
Product Code: PSI-58-455
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-455-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Jurkat cell line lysates (35ug/lane).

Western blot analysis in Jurkat cell line lysates (35ug/lane).

Further Information

Additional Names:
CD226 antigen, DNAX accessory molecule 1, DNAM-1, CD226, CD226, DNAM1
Application Note:
For WB starting dilution is: 1:1000
Background:
CD226 is a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. [provided by RefSeq].
Background References:
  • Lofgren, S.E., et al. Arthritis Rheum. 62(11):3404-3414(2010)
  • Carlsten, M., et al. Leukemia 24(9):1607-1616(2010)
  • Plant, D., et al. Ann. Rheum. Dis. 69(8):1548-1553(2010)
  • Alcina, A., et al. Genes Immun. 11(5):439-445(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CD226 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-335 amino acids from the C-terminal region of human CD226.
NCBI Gene ID #:
10666
NCBI Official Name:
CD226 antigen
NCBI Official Symbol:
CD226
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q15762
Protein GI Number:
317373338
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
Q15762
User NOte:
Optimal dilutions for each application to be determined by the researcher.