ProSci

ELK3 Antibody

Product Code:
 
PSI-58-514
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

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PSI-58-514-400ul400ul£626.00
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Further Information

Additional Names:
ETS domain-containing protein Elk-3, ETS-related protein ERP, ETS-related protein NET, Serum response factor accessory protein 2, SAP-2, SRF accessory protein 2, ELK3, NET, SAP2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present.
Background References:
  • Serchov, T., et al. J. Biol. Chem. 285(28):21223-21232(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Li, B., et al. Tohoku J. Exp. Med. 216(2):139-147(2008)
  • Wasylyk, C., et al. Cancer Res. 68(5):1275-1283(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ELK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the N-terminal region of human ELK3.
NCBI Gene ID #:
2004
NCBI Official Name:
ETS domain-containing protein Elk-3
NCBI Official Symbol:
ELK3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
P41970
Protein GI Number:
116241349
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P41970
User NOte:
Optimal dilutions for each application to be determined by the researcher.