SNRNP70 Antibody

ProSci
Product Code: PSI-58-902
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-902-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in CEM cell line lysates (35ug/lane).

Western blot analysis in CEM cell line lysates (35ug/lane).

Further Information

Additional Names:
U1 small nuclear ribonucleoprotein 70 kDa, U1 snRNP 70 kDa, U1-70K, snRNP70, SNRNP70, RNPU1Z, RPU1, SNRP70, U1AP1
Application Note:
For WB starting dilution is: 1:1000
Background:
SNRNP70 mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.
Background References:
  • Spiluttini, B., et al. J. Cell. Sci. 123 (PT 12), 2085-2093 (2010) :
  • Tzang, B.S., et al. J. Biomed. Sci. 17, 40 (2010) :
  • Parente Costa, L., et al. J. Autoimmun. 33(2):121-124(2009)
  • Hernandez, H., et al. PLoS ONE(9), E7202 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This SNRNP70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human SNRNP70.
NCBI Gene ID #:
6625
NCBI Official Name:
U1 small nuclear ribonucleoprotein 70 kDa
NCBI Official Symbol:
SNRNP70
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
P08621
Protein GI Number:
13635663
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P08621
User NOte:
Optimal dilutions for each application to be determined by the researcher.