HLA-DQA2 Antibody
| Code | Size | Price |
|---|
| PSI-60-924-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
HLA class II histocompatibility antigen, DQ alpha 2 chain, DX alpha chain, HLA class II histocompatibility antigen, DQ(6) alpha chain, HLA-DQA1, MHC class II DQA2, HLA-DQA2, HLA-DXA
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene belongs to the HLA class II alpha chain family.
The encoded protein forms a heterodimer with a class II beta chain.
It is located in intracellular vesicles and plays a central role in
the peptide loading of MHC class II molecules by helping to release
the CLIP molecule from the peptide binding site. Class II molecules
are expressed in antigen presenting cells (B lymphocytes, dendritic
cells, macrophages) and are used to present antigenic peptides on
the cell surface to be recognized by CD4 T-cells. [provided by
RefSeq].
Background References:
- Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)
- Hor, H., et al. Nat. Genet. 42(9):786-789(2010)
- Petukhova, L., et al. Nature 466(7302):113-117(2010)
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HLA-DQA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human HLA-DQA2.
NCBI Gene ID #:
3118
NCBI Official Name:
HLA class II histocompatibility antigen, DQ alpha 2 chain
NCBI Official Symbol:
HLA-DQA2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
P01906
Protein GI Number:
122192
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P01906
User NOte:
Optimal dilutions for each application to be determined by the researcher.