CD1C Antibody
| Code | Size | Price |
|---|
| PSI-57-038-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
T-cell surface glycoprotein CD1c, CD1c, CD1C
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the CD1 family of
transmembrane glycoproteins, which are structurally related to the
major histocompatibility complex (MHC) proteins and form
heterodimers with beta-2-microglobulin. The CD1 proteins mediate
the presentation of primarily lipid and glycolipid antigens of self
or microbial origin to T cells. The human genome contains five CD1
family genes organized in a cluster on chromosome 1. The CD1 family
members are thought to differ in their cellular localization and
specificity for particular lipid ligands. The protein encoded by
this gene is broadly distributed throughout the endocytic system
via a tyrosine-based motif in the cytoplasmic tail. Alternatively
spliced transcript variants of this gene have been observed, but
their full-length nature is not known.
Background References:
- Van Brussel, I., et al. J. Immunol. Methods 362 (1-2), 168-175 (2010) :
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Garzon, D., et al. Mol. Immunol. 47 (2-3), 253-260 (2009) :
- Van Rhijn, I., et al. J. Exp. Med. 206(6):1409-1422(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CD1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the C-terminal region of human CD1C.
NCBI Gene ID #:
911
NCBI Official Name:
T-cell surface glycoprotein CD1c
NCBI Official Symbol:
CD1C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
P29017
Protein GI Number:
143811371
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P29017
User NOte:
Optimal dilutions for each application to be determined by the researcher.