FCAR Antibody
| Code | Size | Price |
|---|
| PSI-56-731-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Immunoglobulin alpha Fc receptor, IgA Fc receptor, CD89, FCAR, CD89
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the immunoglobulin gene
superfamily and encodes a receptor for the Fc region of IgA. The
receptor is a transmembrane glycoprotein present on the surface of
myeloid lineage cells such as neutrophils, monocytes, macrophages,
and eosinophils, where it mediates immunologic responses to
pathogens. It interacts with IgA-opsonized targets and triggers
several immunologic defense processes, including phagocytosis,
antibody-dependent cell-mediated cytotoxicity, and stimulation of
the release of inflammatory mediators. Multiple alternatively
spliced transcript variants encoding different isoforms have been
described for this gene.
Background References:
- Vuong, M.T., et al. Kidney Int. (2010) In press :
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Peng, M., et al. Cell Res. 20(2):223-237(2010)
- Kobayashi, T., et al. J. Dent. Res. 88(12):1137-1141(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FCAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-84 amino acids from the Central region of human FCAR.
NCBI Gene ID #:
2204
NCBI Official Name:
Immunoglobulin alpha Fc receptor
NCBI Official Symbol:
FCAR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
P24071
Protein GI Number:
119860
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P24071
User NOte:
Optimal dilutions for each application to be determined by the researcher.