FOXN1 Antibody
Code | Size | Price |
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PSI-56-203-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Forkhead box protein N1, Winged-helix transcription factor nude, FOXN1, RONU, WHN
Application Note:
For WB starting dilution is: 1:2000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
Mutations in the winged-helix transcription factor gene at
the nude locus in mice and rats produce the pleiotropic phenotype
of hairlessness and athymia, resulting in a severely compromised
immune system. This gene is orthologous to the mouse and rat genes
and encodes a similar DNA-binding transcription factor that is
thought to regulate keratin gene expression. A mutation in this
gene has been correlated with T-cell immunodeficiency, the skin
disorder congenital alopecia, and nail dystrophy. Alternative
splicing in the 5' UTR of this gene has been observed. [provided by
RefSeq].
Background References:
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- Mandinova, A., et al. J. Clin. Invest. 119(10):3127-3137(2009)
- Pignata, C., et al. Adv. Exp. Med. Biol. 665, 195-206 (2009) :
- Weiner, L., et al. Cell 130(5):932-942(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This FOXN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-378 amino acids from the Central region of human FOXN1.
NCBI Gene ID #:
8456
NCBI Official Name:
Forkhead box protein N1
NCBI Official Symbol:
FOXN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
69 kDa
Protein Accession #:
O15353
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
O15353
User NOte:
Optimal dilutions for each application to be determined by the researcher.