LILRA2 Antibody
| Code | Size | Price |
|---|
| PSI-55-193-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Leukocyte immunoglobulin-like receptor subfamily A member 2, CD85 antigen-like family member H, Immunoglobulin-like transcript 1, ILT-1, Leukocyte immunoglobulin-like receptor 7, LIR-7, CD85h, LILRA2, ILT1, LIR7
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
Leukocyte Ig-like receptors (LIRs) are a family of
immunoreceptors expressed predominantly on monocytes and B cells
and at lower levels on dendritic cells and natural killer (NK)
cells. All LIRs in subfamily B have an inhibitory function (see,
e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short
cytoplasmic domains lacking an immunoreceptor tyrosine-based
inhibitory motif (ITIM) and with transmembrane regions containing a
charged arginine residue, may initiate stimulatory cascades. One
member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane
region and is presumed to be a soluble receptor.
Background References:
- Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Jones, D.C., et al. Eur. J. Immunol. 39(11):3195-3206(2009)
- Chen, Y., et al. J. Mol. Biol. 386(3):841-853(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LILRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-81 amino acids from the Central region of human LILRA2.
NCBI Gene ID #:
11027
NCBI Official Name:
Leukocyte immunoglobulin-like receptor subfamily A member 2
NCBI Official Symbol:
LILRA2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
Q8N149
Protein GI Number:
37537906
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
Q8N149
User NOte:
Optimal dilutions for each application to be determined by the researcher.