CFD Antibody
| Code | Size | Price |
|---|
| PSI-56-222-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Complement factor D, Adipsin, C3 convertase activator, Properdin factor D, CFD, DF, PFD
Application Note:
For WB starting dilution is: 1:2000
Background:
The protein encoded by this gene is a member of the
trypsin family of peptidases. The encoded protein is a component of
the alternative complement pathway best known for its role in
humoral suppression of infectious agents. This protein is also a
serine protease that is secreted by adipocytes into the
bloodstream. Finally, the encoded protein has a high level of
expression in fat, suggesting a role for adipose tissue in immune
system biology.
Background References:
- Bailey, S.D., et al. Diabetes Care (2010) In press :
- Hietaharju, A., et al. Eur. J. Neurol. 17(2):332-334(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Ciprandi, G., et al. Int. Immunopharmacol. 9(12):1460-1463(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Pig, Bovine
Immunogen:
This CFD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-99 amino acids from the N-terminal region of human CFD.
NCBI Gene ID #:
1675
NCBI Official Name:
Complement factor D
NCBI Official Symbol:
CFD
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
P00746
Protein GI Number:
158515408
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P00746
User NOte:
Optimal dilutions for each application to be determined by the researcher.