C9 Antibody

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ProSci
Product Code: PSI-57-269
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-269-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution + human liver lysate Lysates/proteins at 20 ug per lane.
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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the detected the C9 protein (arrow).
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Western Blot at 1:1000 dilution + human liver lysate Lysates/proteins at 20 ug per lane.
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the detected the C9 protein (arrow).

Documents

Further Information

Additional Names:
Complement component C9, Complement component C9a, Complement component C9b, C9
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq].
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
  • Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
  • Bunkenborg, J., et al. Proteomics 4(2):454-465(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This C9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-220 amino acids from the Central region of human C9.
NCBI Gene ID #:
735
NCBI Official Name:
Complement component C9
NCBI Official Symbol:
C9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
P02748
Protein GI Number:
1352108
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P02748
User NOte:
Optimal dilutions for each application to be determined by the researcher.