CD1A Antibody
| Code | Size | Price |
|---|
| PSI-57-104-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
T-cell surface glycoprotein CD1a, T-cell surface antigen T6/Leu-6, hTa1 thymocyte antigen, CD1a, CD1A
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the CD1 family of
transmembrane glycoproteins, which are structurally related to the
major histocompatibility complex (MHC) proteins and form
heterodimers with beta-2-microglobulin. The CD1 proteins mediate
the presentation of primarily lipid and glycolipid antigens of self
or microbial origin to T cells. The human genome contains five CD1
family genes organized in a cluster on chromosome 1. The CD1 family
members are thought to differ in their cellular localization and
specificity for particular lipid ligands. The protein encoded by
this gene localizes to the plasma membrane and to recycling
vesicles of the early endocytic system. Alternatively spliced
transcript variants have been observed, but their biological
validity has not been determined.
Background References:
- Zeissig, S., et al. J. Clin. Invest. 120(8):2889-2899(2010)
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Valencia, J., et al. J. Leukoc. Biol. 87(3):405-414(2010)
- Cernadas, M., et al. J. Immunol. 184(3):1235-1241(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CD1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the Central region of human CD1A.
NCBI Gene ID #:
909
NCBI Official Name:
T-cell surface glycoprotein CD1a
NCBI Official Symbol:
CD1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
P06126
Protein GI Number:
288558852
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P06126
User NOte:
Optimal dilutions for each application to be determined by the researcher.