MBL2 Antibody
| Code | Size | Price |
|---|
| PSI-57-234-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Mannose-binding protein C, MBP-C, Collectin-1, MBP1, Mannan-binding protein, Mannose-binding lectin, MBL2, COLEC1, MBL
Application Note:
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes the soluble mannose-binding lectin or
mannose-binding protein found in serum. The protein encoded belongs
to the collectin family and is an important element in the innate
immune system. The protein recognizes mannose and
N-acetylglucosamine on many microorganisms, and is capable of
activating the classical complement pathway. Deficiencies of this
gene have been associated with susceptibility to autoimmune and
infectious diseases.
Background References:
- Auriti, C., et al. Hum. Immunol. 71(11):1084-1088(2010)
- Fraser, D.A., et al. J. Immunol. 185(7):3932-3939(2010)
- de Wit, E., et al. Mamm. Genome (2010) In press :
- Filho, R.M., et al. Viral Immunol. 23(4):449-453(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MBL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-202 amino acids from the C-terminal region of human MBL2.
NCBI Gene ID #:
4153
NCBI Official Name:
Mannose-binding protein C
NCBI Official Symbol:
MBL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
P11226
Protein GI Number:
126676
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P11226
User NOte:
Optimal dilutions for each application to be determined by the researcher.