AZU1 Antibody
| Code | Size | Price |
|---|
| PSI-58-140-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Azurocidin, Cationic antimicrobial protein CAP37, Heparin-binding protein, HBP, AZU1
Application Note:
For WB starting dilution is: 1:1000
Background:
Azurophil granules, specialized lysosomes of the
neutrophil, contain at least 10 proteins implicated in the killing
of microorganisms. The protein encoded by this gene is an azurophil
granule antibiotic protein, with monocyte chemotactic and
antibacterial activity. It is also an important multifunctional
inflammatory mediator. This encoded protein is a member of the
serine protease gene family but it is not a serine proteinase,
because the active site serine and histidine residues are replaced.
The genes encoding this protein, neutrophil elastase 2, and
proteinase 3 are in a cluster located at chromosome 19pter. All 3
genes are expressed coordinately and their protein products are
packaged together into azurophil granules during neutrophil
differentiation.
Background References:
- Changho, S., et al. Pathol. Res. Pract. 206(5):314-317(2010)
- Linder, A., et al. J. Invest. Dermatol. 130(5):1365-1372(2010)
- Segat, L., et al. Vaccine 28(10):2201-2206(2010)
- Wilker, E., et al. Environ. Health Perspect. 117(6):935-940(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This AZU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of human AZU1.
NCBI Gene ID #:
566
NCBI Official Name:
Azurocidin
NCBI Official Symbol:
AZU1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
P20160
Protein GI Number:
416746
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,
Swissprot #:
P20160
User NOte:
Optimal dilutions for each application to be determined by the researcher.