CCR4 Antibody
| Code | Size | Price |
|---|
| PSI-59-665-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4, CCR-4, CCR4, K5-5, CD194, CCR4, CMKBR4
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the
G-protein-coupled receptor family . It is a receptor for the CC
chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group
of small polypeptide, structurally related molecules that regulate
cell trafficking of various types of leukocytes. The chemokines
also play fundamental roles in the development, homeostasis, and
function of the immune system, and they have effects on cells of
the central nervous system as well as on endothelial cells involved
in angiogenesis or angiostasis.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
- Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
- Klapa, S., et al. Clin. Exp. Rheumatol. 28 (1 SUPPL 57), 72-80 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the C-terminal region of human CCR4.
NCBI Gene ID #:
1233
NCBI Official Name:
C-C chemokine receptor type 4
NCBI Official Symbol:
CCR4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
P51679
Protein GI Number:
1705894
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Growth Factor
Swissprot #:
P51679
User NOte:
Optimal dilutions for each application to be determined by the researcher.