ICA1 Antibody
| Code | Size | Price |
|---|
| PSI-58-732-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Islet cell autoantigen 1, 69 kDa islet cell autoantigen, ICA69, Islet cell autoantigen p69, ICAp69, p69, ICA1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein with an arfaptin homology
domain that is found both in the cytosol and as membrane-bound form
on the Golgi complex and immature secretory granules. This protein
is believed to be an autoantigen in insulin-dependent diabetes
mellitus and primary Sjogren's syndrome. Alternatively spliced
variants which encode different protein isoforms have been
described; however, not all variants have been fully characterized.
Background References:
- Jin, Y., et al. Nat. Genet. 42(7):576-578(2010)
- Rose, J. Phd, et al. Mol. Med. (2010) In press :
- Buffa, L., et al. Eur. J. Cell Biol. 87(4):197-209(2008)
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This ICA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-111 amino acids from the N-terminal region of human ICA1.
NCBI Gene ID #:
3382
NCBI Official Name:
Islet cell autoantigen 1
NCBI Official Symbol:
ICA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
Q05084
Protein GI Number:
20141584
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Neuroscience
Swissprot #:
Q05084
User NOte:
Optimal dilutions for each application to be determined by the researcher.