CXCL11 Antibody
| Code | Size | Price |
|---|
| PSI-58-013-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11, CXCL11, ITAC, SCYB11, SCYB9B
Application Note:
For WB starting dilution is: 1:1000
Background:
Chemokines are a group of small (approximately 8 to 14
kD), mostly basic, structurally related molecules that regulate
cell trafficking of various types of leukocytes through
interactions with a subset of 7-transmembrane, G protein-coupled
receptors. Chemokines also play fundamental roles in the
development, homeostasis, and function of the immune system, and
they have effects on cells of the central nervous system as well as
on endothelial cells involved in angiogenesis or angiostasis.
Chemokines are divided into 2 major subfamilies, CXC and CC. This
gene is a CXC member of the chemokine superfamily. Its encoded
protein induces a chemotactic response in activated T-cells and is
the dominant ligand for CXC receptor-3. The gene encoding this
protein contains 4 exons and at least three polyadenylation signals
which might reflect cell-specific regulation of expression.
IFN-gamma is a potent inducer of transcription of this gene.
Background References:
- Rot, A. Front. Biosci. 15, 645-660 (2010) :
- Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)
- Kouroumalis, A., et al. J. Immunol. 175(8):5403-5411(2005)
- Booth, V., et al. Protein Sci. 13(8):2022-2028(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CXCL11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-93 amino acids from the C-terminal region of human CXCL11.
NCBI Gene ID #:
6373
NCBI Official Name:
C-X-C motif chemokine 11
NCBI Official Symbol:
CXCL11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
10 kDa
Protein Accession #:
O14625
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Neuroscience
Swissprot #:
O14625
User NOte:
Optimal dilutions for each application to be determined by the researcher.