C1QC Antibody
| Code | Size | Price |
|---|
| PSI-56-126-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Complement C1q subcomponent subunit C, C1QC, C1QG
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Background:
This gene encodes a major constituent of the human
complement subcomponent C1q. C1q associates with C1r and C1s in
order to yield the first component of the serum complement system.
A deficiency in C1q has been associated with lupus erythematosus
and glomerulonephritis. C1q is composed of 18 polypeptide chains:
six A-chains, six B-chains, and six C-chains. Each chain contains a
collagen-like region located near the N-terminus, and a C-terminal
globular region. The A-, B-, and C-chains are arranged in the order
A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of
human complement subcomponent C1q. Alternatively spliced transcript
variants that encode the same protein have been found for this
gene.
Background References:
- Fraser, D.A., et al. J. Immunol. 185(7):3932-3939(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Rafiq, S., et al. Clin. Exp. Immunol. 161(2):284-289(2010)
- Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This C1QC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the Central region of human C1QC.
NCBI Gene ID #:
714
NCBI Official Name:
Complement C1q subcomponent subunit C
NCBI Official Symbol:
C1QC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
P02747
Protein GI Number:
20178281
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Neuroscience
Swissprot #:
P02747
User NOte:
Optimal dilutions for each application to be determined by the researcher.