CD97 Antibody
| Code | Size | Price |
|---|
| PSI-57-256-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
CD97 antigen, Leukocyte antigen CD97, CD97, CD97 antigen subunit alpha, CD97 antigen subunit beta, CD97
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene is a member of the EGF-TM7 family of class II
seven-span transmembrane (7-TM) molecules, likely encoded by a gene
cluster on the short arm of chromosome 19. The encoded product is a
glycoprotein that is present on the surface of most activated
leukocytes and spans the membrane seven times, which is a defining
feature of G protein-coupled receptors. The protein has an extended
extracellular region with several N-terminal epidermal growth
factor (EGF)-like domains, which mediate binding to its cellular
ligand, decay accelerating factor (DAF, CD55), a regulatory protein
of the complement cascade. The presence of structural features
characteristic of extracellular matrix proteins and transmembrane
proteins suggests that this protein is a receptor involved in both
cell adhesion and signaling processes early after leukocyte
activation. Alternative splicing has been observed for this gene
and three variants have been found.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Liu, D., et al. Int. J. Oncol. 36(6):1401-1408(2010)
- Han, S.L., et al. IntColorectal Dis 25(6):695-702(2010)
- van Eijk, M., et al. Immunol. Lett. 129(2):64-71(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CD97 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 707-736 amino acids from the C-terminal region of human CD97.
NCBI Gene ID #:
976
NCBI Official Name:
CD97 antigen
NCBI Official Symbol:
CD97
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
92 kDa
Protein Accession #:
P48960
Protein GI Number:
90110013
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Neuroscience,Signal Transduction,Growth Factor
Swissprot #:
P48960
User NOte:
Optimal dilutions for each application to be determined by the researcher.