MRPS31 Antibody
| Code | Size | Price |
|---|
| PSI-60-091-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
28S ribosomal protein S31, mitochondrial, MRP-S31, S31mt, Imogen 38, MRPS31, IMOGN38
Application Note:
For WB starting dilution is: 1:1000
Background:
Mammalian mitochondrial ribosomal proteins are encoded by
nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a
small 28S subunit and a large 39S subunit. They have an estimated
75% protein to rRNA composition compared to prokaryotic ribosomes,
where this ratio is reversed. Another difference between mammalian
mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the
mitoribosome differ greatly in sequence, and sometimes in
biochemical properties, which prevents easy recognition by sequence
homology. The 28S subunit of the mammalian mitoribosome may play a
crucial and characteristic role in translation initiation. This
gene encodes a 28S subunit protein that has also been associated
with type 1 diabetes; however, its relationship to the etiology of
this disease remains to be clarified. Pseudogenes corresponding to
this gene have been found on chromosomes 3 and 13. [provided by
RefSeq].
Background References:
- Dunham, A., et al. Nature 428(6982):522-528(2004)
- Zhang, Z., et al. Genomics 81(5):468-480(2003)
- Tchernev, V.T., et al. Mol. Med. 8(1):56-64(2002)
- Cavdar Koc, E., et al. J. Biol. Chem. 276(22):19363-19374(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MRPS31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-247 amino acids from the Central region of human MRPS31.
NCBI Gene ID #:
10240
NCBI Official Name:
28S ribosomal protein S31, mitochondrial
NCBI Official Symbol:
MRPS31
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
Q92665
Protein GI Number:
93186129
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Obesity
Swissprot #:
Q92665
User NOte:
Optimal dilutions for each application to be determined by the researcher.