LTB4R2 Antibody

ProSci
Product Code: PSI-58-279
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-279-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A549 cell line lysates (35ug/lane).

Western blot analysis in A549 cell line lysates (35ug/lane).

Further Information

Additional Names:
Leukotriene B4 receptor 2, LTB4-R 2, LTB4-R2, LTB4 receptor JULF2, Leukotriene B4 receptor BLT2, Seven transmembrane receptor BLTR2, LTB4R2, BLT2R, BLTR2
Application Note:
For WB starting dilution is: 1:1000
Background:
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.
Background References:
  • Kim, G.Y., et al. J. Immunol. 184(7):3946-3954(2010)
  • Ryu, H.C., et al. J. Invest. Dermatol. 130(4):1095-1106(2010)
  • Choi, J.A., et al. Carcinogenesis 31(4):543-551(2010)
  • Cho, K.J., et al. Am. J. Respir. Cell Mol. Biol. 42(3):294-303(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LTB4R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-361 amino acids from the C-terminal region of human LTB4R2.
NCBI Gene ID #:
56413
NCBI Official Name:
Leukotriene B4 receptor 2
NCBI Official Symbol:
LTB4R2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
Q9NPC1
Protein GI Number:
23821812
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Obesity,Growth Factor
Swissprot #:
Q9NPC1
User NOte:
Optimal dilutions for each application to be determined by the researcher.