FOLR2 Antibody
| Code | Size | Price |
|---|
| PSI-58-204-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBP, FOLR2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the folate
receptor (FOLR) family, and these genes exist in a cluster on
chromosome 11. Members of this gene family have a high affinity for
folic acid and for several reduced folic acid derivatives, and they
mediate delivery of 5-methyltetrahydrofolate to the interior of
cells. This protein has a 68% and 79% sequence homology with the
FOLR1 and FOLR3 proteins, respectively. Although this protein was
originally thought to be specific to placenta, it can also exist in
other tissues, and it may play a role in the transport of
methotrexate in synovial macrophages in rheumatoid arthritis
patients. Multiple transcript variants that encode the same protein
have been found for this gene.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- O'Byrne, M.R., et al. Birth Defects Res. PartClin. Mol. Teratol. 88(8):689-694(2010)
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-44 amino acids from the N-terminal region of human FOLR2.
NCBI Gene ID #:
2350
NCBI Official Name:
Folate receptor beta
NCBI Official Symbol:
FOLR2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Protein Accession #:
P14207
Protein GI Number:
116241366
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Obesity,Signal Transduction
Swissprot #:
P14207
User NOte:
Optimal dilutions for each application to be determined by the researcher.