PLA2G5 Antibody
| Code | Size | Price |
|---|
| PSI-57-971-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Calcium-dependent phospholipase A2, Group V phospholipase A2, PLA2-10, Phosphatidylcholine 2-acylhydrolase 5, PLA2G5
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene is a member of the secretory phospholipase A2
family. It is located in a tightly-linked cluster of secretory
phospholipase A2 genes on chromosome 1. The encoded enzyme
catalyzes the hydrolysis of membrane phospholipids to generate
lysophospholipids and free fatty acids including arachidonic acid.
It preferentially hydrolyzes linoleoyl-containing
phosphatidylcholine substrates. Secretion of this enzyme is thought
to induce inflammatory responses in neighboring cells.
Alternatively spliced transcript variants have been found, but
their full-length nature has not been determined. [provided by
RefSeq].
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Chattopadhyay, I., et al. Mutat. Res. 696(2):130-138(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Wootton, P.T., et al. Hum. Mol. Genet. 16(12):1437-1444(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PLA2G5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the C-terminal region of human PLA2G5.
NCBI Gene ID #:
5322
NCBI Official Name:
Calcium-dependent phospholipase A2
NCBI Official Symbol:
PLA2G5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
16 kDa
Protein Accession #:
P39877
Protein GI Number:
730258
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Obesity,Signal Transduction
Swissprot #:
P39877
User NOte:
Optimal dilutions for each application to be determined by the researcher.