IL23R Antibody
| Code | Size | Price |
|---|
| PSI-58-876-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Interleukin-23 receptor, IL-23 receptor, IL-23R, IL23R
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a subunit of the
receptor for IL23A/IL23. This protein pairs with the receptor
molecule IL12RB1/IL12Rbeta1, and both are required for IL23A
signaling. This protein associates constitutively with Janus kinase
2 (JAK2), and also binds to transcription activator STAT3 in a
ligand-dependent manner.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Chen, J., et al. Mol. Carcinog. 49(10):862-868(2010)
- Mizuki, N., et al. Nat. Genet. 42(8):703-706(2010)
- Remmers, E.F., et al. Nat. Genet. 42(8):698-702(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This IL23R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the C-terminal region of human IL23R.
NCBI Gene ID #:
149233
NCBI Official Name:
Interleukin-23 receptor
NCBI Official Symbol:
IL23R
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
72 kDa
Protein Accession #:
Q5VWK5
Protein GI Number:
311033431
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q5VWK5
User NOte:
Optimal dilutions for each application to be determined by the researcher.