NKAP Antibody
| Code | Size | Price |
|---|
| PSI-56-401-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
NF-kappa-B-activating protein, NKAP
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that is involved in the
activation of the ubiquitous transcription factor NF-kappaB. This
protein is associated with the the histone deacetylase HDAC3 and
with the Notch corepressor complex, and it thereby acts as a
transcriptional repressor of Notch target genes. It is also
required for alphabeta T cell development. A related pseudogene has
been identified on chromosome X, while a related and intronless
retrocopy, which has an intact CDS and may be functional, is
located on chromosome 6.
Background References:
- D'Addabbo, A., et al. Artif Intell Med 46(2):131-138(2009)
- Pajerowski, A.G., et al. Immunity 30(5):696-707(2009)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
- Chen, D., et al. Biochem. Biophys. Res. Commun. 310(3):720-724(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This NKAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of human NKAP.
NCBI Gene ID #:
79576
NCBI Official Name:
NF-kappa-B-activating protein
NCBI Official Symbol:
NKAP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
Q8N5F7
Protein GI Number:
74728990
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q8N5F7
User NOte:
Optimal dilutions for each application to be determined by the researcher.