CLC Antibody
| Code | Size | Price |
|---|
| PSI-58-277-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Galectin-10, Gal-10, Charcot-Leyden crystal protein, CLC, Eosinophil lysophospholipase, Lysolecithin acylhydrolase, CLC, LGALS10, LGALS10A
Application Note:
For WB starting dilution is: 1:1000
Background:
Lysophospholipases are enzymes that act on biological
membranes to regulate the multifunctional lysophospholipids. The
protein encoded by this gene is a lysophospholipase expressed in
eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to
glycerophosphocholine and a free fatty acid. This protein may
possess carbohydrate or IgE-binding activities. It is both
structurally and functionally related to the galectin family of
beta-galactoside binding proteins. It may be associated with
inflammation and some myeloid leukemias.
Background References:
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Bryborn, M., et al. Allergy 65(2):220-228(2010)
- De Re, V., et al. Ann. N. Y. Acad. Sci. 1173, 357-364 (2009) :
- Than, N.G., et al. Proc. Natl. Acad. Sci. U.S.A. 106(24):9731-9736(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CLC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the C-terminal region of human CLC.
NCBI Gene ID #:
1178
NCBI Official Name:
Galectin-10
NCBI Official Symbol:
CLC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
16 kDa
Protein Accession #:
Q05315
Protein GI Number:
317373429
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q05315
User NOte:
Optimal dilutions for each application to be determined by the researcher.