LAX1 Antibody
Code | Size | Price |
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PSI-60-025-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Lymphocyte transmembrane adapter 1, Linker for activation of X cells, Membrane-associated adapter protein LAX, LAX1, LAX
Application Note:
For WB starting dilution is: 1:1000
Background:
LAX1 negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
Background References:
- Ehret, G.B., et al. Eur. J. Hum. Genet. 17(12):1650-1657(2009)
- Shapiro, M.J., et al. J. Immunol. 181(10):7055-7061(2008)
- Zhu, M., et al. J. Immunol. 174(9):5612-5619(2005)
- Zhu, M., et al. J. Biol. Chem. 277(48):46151-46158(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-398 amino acids from the C-terminal region of human LAX1.
NCBI Gene ID #:
54900
NCBI Official Name:
Lymphocyte transmembrane adapter 1
NCBI Official Symbol:
LAX1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
Q8IWV1
Protein GI Number:
74728197
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q8IWV1
User NOte:
Optimal dilutions for each application to be determined by the researcher.