Mouse Irak4 Antibody
| Code | Size | Price |
|---|
| PSI-57-510-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Interleukin-1 receptor-associated kinase 4, IRAK-4, Irak4
Application Note:
For WB starting dilution is: 1:1000
Background:
Irak4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1 (By similarity).
Background References:
- Erdman, L.K., et al. J. Immunol. 183(10):6452-6459(2009)
- Maekawa, Y., et al. Circulation 120(14):1401-1414(2009)
- Bauernfeind, F.G., et al. J. Immunol. 183(2):787-791(2009)
- Staschke, K.A., et al. J. Immunol. 183(1):568-577(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Irak4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-449 amino acids from the C-terminal region of mouse Irak4.
NCBI Gene ID #:
266632
NCBI Official Name:
Interleukin-1 receptor-associated kinase 4
NCBI Official Symbol:
Irak4
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
Q8R4K2
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q8R4K2
User NOte:
Optimal dilutions for each application to be determined by the researcher.