IL1R2 Antibody
| Code | Size | Price |
|---|
| PSI-55-587-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Interleukin-1 receptor type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 antigen-like family member B, CDw121b, IL-1 type II receptor, Interleukin-1 receptor beta, IL-1R-beta, Interleukin-1 receptor type II, CD121b, Interleukin-1 receptor type 2, membrane form, mIL-1R2, mIL-1RII, Interleukin-1 receptor type 2, soluble form, sIL-1R2, sIL-1RII, IL1R2, IL1RB
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a cytokine receptor
that belongs to the interleukin 1 receptor family. This protein
binds interleukin alpha (IL1A), interleukin beta (IL1B), and
interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy
receptor that inhibits the activity of its ligands. Interleukin 4
(IL4) is reported to antagonize the activity of interleukin 1 by
inducing the expression and release of this cytokine. This gene and
three other genes form a cytokine receptor gene cluster on
chromosome 2q12. Two alternatively spliced transcript variants
encoding the same protein have been reported.
Background References:
- Giroux, S., et al. Bone 47(5):975-981(2010)
- Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Chen, C., et al. Rheumatol. Int. (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This IL1R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-300 amino acids from the Central region of human IL1R2.
NCBI Gene ID #:
7850
NCBI Official Name:
Interleukin-1 receptor type 2
NCBI Official Symbol:
IL1R2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
P27930
Protein GI Number:
124310
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
P27930
User NOte:
Optimal dilutions for each application to be determined by the researcher.