SKAP1 Antibody
| Code | Size | Price |
|---|
| PSI-60-148-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Src kinase-associated phosphoprotein 1, Src family-associated phosphoprotein 1, Src kinase-associated phosphoprotein of 55 kDa, SKAP-55, pp55, SKAP1, SCAP1, SKAP55
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a T cell adaptor protein, a class of
intracellular molecules with modular domains capable of recruiting
additional proteins but that exhibit no intrinsic enzymatic
activity. The encoded protein contains a unique N-terminal region
followed by a PH domain and C-terminal SH3 domain. Along with the
adhesion and degranulation-promoting adaptor protein, the encoded
protein plays a critical role in inside-out signaling by coupling
T-cell antigen receptor stimulation to the activation of integrins.
Background References:
- Goode, E.L., et al. Nat. Genet. 42(10):874-879(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Raab, M., et al. Immunity 32(4):541-556(2010)
- Lehmann, R., et al. Proteomics 9(23):5288-5295(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SKAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the C-terminal region of human SKAP1.
NCBI Gene ID #:
8631
NCBI Official Name:
Src kinase-associated phosphoprotein 1
NCBI Official Symbol:
SKAP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
Q86WV1
Protein GI Number:
269849660
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q86WV1
User NOte:
Optimal dilutions for each application to be determined by the researcher.