TRIM22 Antibody
Code | Size | Price |
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PSI-60-591-400ul | 400ul | £626.00 |
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Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
E3 ubiquitin-protein ligase TRIM22, 632-, 50 kDa-stimulated trans-acting factor, RING finger protein 94, Staf-50, Tripartite motif-containing protein 22, TRIM22, RNF94, STAF50
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the
tripartite motif (TRIM) family. The TRIM motif includes three
zinc-binding domains, a RING, a B-box type 1 and a B-box type 2,
and a coiled-coil region. This protein localizes to the cytoplasm
and its expression is induced by interferon. The protein
down-regulates transcription from the HIV-1 LTR promoter region,
suggesting that function of this protein may be to mediate
interferon's antiviral effects.
Background References:
- Kajaste-Rudnitski, A., et al. Amino Acids 39(1):1-9(2010)
- Petersson, J., et al. Exp. Cell Res. 316(4):568-579(2010)
- Ovsyannikova, I.G., et al. Hum. Genet. 127(2):207-221(2010)
- Ovsyannikova, I.G., et al. J. Infect. Dis. 201(2):207-213(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TRIM22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human TRIM22.
NCBI Gene ID #:
10346
NCBI Official Name:
E3 ubiquitin-protein ligase TRIM22
NCBI Official Symbol:
TRIM22
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
Q8IYM9
Protein GI Number:
47606181
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q8IYM9
User NOte:
Optimal dilutions for each application to be determined by the researcher.