MAEA Antibody
| Code | Size | Price |
|---|
| PSI-59-522-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Macrophage erythroblast attacher, Cell proliferation-inducing gene 5 protein, Erythroblast macrophage protein, Human lung cancer oncogene 10 protein, HLC-10, MAEA, EMP
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene product mediates the attachment of erythroblasts
to macrophages. This attachment promotes terminal maturation and
enucleation of erythroblasts, presumably by suppressing apoptosis.
This protein is an integral membrane protein with the N-terminus on
the extracellular side and the C-terminus on the cytoplasmic side
of the cell. Two immunologically related isoforms of erythroblast
macrophage protein with apparent molecular weights of 33 kD and 36
kD were detected in macrophage membranes; this gene encodes the
larger isoform. Multiple alternatively spliced transcript variants
encoding distinct isoforms have been found for this gene, but the
biological validity of some variants has not been determined.
Background References:
- Kobayashi, N., et al. Gene 396(2):236-247(2007)
- Bala, S., et al. Biochem. Biophys. Res. Commun. 342(4):1040-1048(2006)
- Hanspal, M., et al. Blood 92(8):2940-2950(1998)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Zebrafish, Monkey, Mouse, Rat, Xenopus
Immunogen:
This MAEA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-42 amino acids from the N-terminal region of human MAEA.
NCBI Gene ID #:
10296
NCBI Official Name:
Macrophage erythroblast attacher
NCBI Official Symbol:
MAEA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
Q7L5Y9
Protein GI Number:
74754297
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q7L5Y9
User NOte:
Optimal dilutions for each application to be determined by the researcher.