CD86 Antibody
| Code | Size | Price |
|---|
| PSI-58-262-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
T-lymphocyte activation antigen CD86, Activation B7-2 antigen, B70, BU63, CTLA-4 counter-receptor B72, FUN-1, CD86, CD86, CD28LG2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a type I membrane protein that is a
member of the immunoglobulin superfamily. This protein is expressed
by antigen-presenting cells, and it is the ligand for two proteins
at the cell surface of T cells, CD28 antigen and cytotoxic
T-lymphocyte-associated protein 4. Binding of this protein with
CD28 antigen is a costimulatory signal for activation of the
T-cell. Binding of this protein with cytotoxic
T-lymphocyte-associated protein 4 negatively regulates T-cell
activation and diminishes the immune response. Alternative splicing
results in two transcript variants encoding different isoforms.
Additional transcript variants have been described, but their
full-length sequences have not been determined. [provided by
RefSeq].
Background References:
- Liu, Y., et al. Hum. Immunol. 71(11):1141-1146(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Grujic, M., et al. J. Immunol. 185(3):1730-1743(2010)
- Dalla-Costa, R., et al. Hum. Immunol. 71(8):809-817(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CD86 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-298 amino acids from the C-terminal region of human CD86.
NCBI Gene ID #:
942
NCBI Official Name:
T-lymphocyte activation antigen CD86
NCBI Official Symbol:
CD86
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
P42081
Protein GI Number:
317373339
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
P42081
User NOte:
Optimal dilutions for each application to be determined by the researcher.