CCL7 Antibody

ProSci
Product Code: PSI-58-765
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-765-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).

Western blot analysis in K562 cell line lysates (35ug/lane).

Further Information

Additional Names:
C-C motif chemokine 7, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, MCP-3, NC28, Small-inducible cytokine A7, CCL7, MCP3, SCYA6, SCYA7
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q.
Background References:
  • McGovern, D.P., et al. Hum. Mol. Genet. 19(17):3468-3476(2010)
  • Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
  • Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
  • Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CCL7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the Central region of human CCL7.
NCBI Gene ID #:
6354
NCBI Official Name:
C-C motif chemokine 7
NCBI Official Symbol:
CCL7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
11 kDa
Protein Accession #:
P80098
Protein GI Number:
1170890
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
P80098
User NOte:
Optimal dilutions for each application to be determined by the researcher.