SELE Antibody
| Code | Size | Price |
|---|
| PSI-59-653-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
E-selectin, CD62 antigen-like family member E, Endothelial leukocyte adhesion molecule 1, ELAM-1, Leukocyte-endothelial cell adhesion molecule 2, LECAM2, CD62E, SELE, ELAM1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is found in
cytokine-stimulated endothelial cells and is thought to be
responsible for the accumulation of blood leukocytes at sites of
inflammation by mediating the adhesion of cells to the vascular
lining. It exhibits structural features such as the presence of
lectin- and EGF-like domains followed by short consensus repeat
(SCR) domains that contain 6 conserved cysteine residues. These
proteins are part of the selectin family of cell adhesion
molecules. Adhesion molecules participate in the interaction
between leukocytes and the endothelium and appear to be involved in
the pathogenesis of atherosclerosis.
Background References:
- Palmer, C.N., et al. Diabetes 59(11):2945-2948(2010)
- Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Wayman, A.M., et al. Biophys. J. 99(4):1166-1174(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TRAIL antibody is generated from rabbits immunized with a recombinant protein from the human TRAIL.
NCBI Gene ID #:
6401
NCBI Official Name:
E-selectin
NCBI Official Symbol:
SELE
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
Protein Accession #:
P16581
Protein GI Number:
126180
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
P16581
User NOte:
Optimal dilutions for each application to be determined by the researcher.