FCGR2B Antibody
| Code | Size | Price |
|---|
| PSI-57-401-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Low affinity immunoglobulin gamma Fc region receptor II-b, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, CD32, FCGR2B, CD32, FCG2, IGFR2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a low affinity
receptor for the Fc region of immunoglobulin gamma complexes. The
encoded protein is involved in the phagocytosis of immune complexes
and in the regulation of antibody production by B-cells. Variations
in this gene may increase susceptibilty to systemic lupus
erythematosus (SLE). Several transcript variants encoding different
isoforms have been found for this gene.
Background References:
- Prokopec, K.E., et al. Clin. Immunol. 137(3):322-329(2010)
- Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
- Zhang, C.Y., et al. J. Biol. Chem. 285(44):34250-34258(2010)
- Niederer, H.A., et al. Hum. Mol. Genet. 19(16):3282-3294(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FCGR2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the C-terminal region of human FCGR2B.
NCBI Gene ID #:
2213
NCBI Official Name:
Low affinity immunoglobulin gamma Fc region receptor II-b
NCBI Official Symbol:
FCGR2B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
P31994
Protein GI Number:
8039788
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
P31994
User NOte:
Optimal dilutions for each application to be determined by the researcher.